RNA-dependent recruitment of the origin recognition complex

The origin recognition complex (ORC) has an important function in determining the initiation sites of DNA replication. In higher eukaryotes, ORC lacks sequence-specific DNA binding, and the mechanisms of ORC recruitment and origin determination are poorly understood. ORC is recruited with high effic...

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Hlavní autoři: Norseen, Julie, Thomae, Andreas, Sridharan, Venkatesh, Aiyar, Ashok, Schepers, Aloys, Lieberman, Paul M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585170/
https://ncbi.nlm.nih.gov/pubmed/18946490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.221
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