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Interaction between HMGA1a and the origin recognition complex creates site-specific replication origins
In all eukaryotic cells, origins of DNA replication are characterized by the binding of the origin recognition complex (ORC). How ORC is positioned to sites where replication initiates is unknown, because metazoan ORC binds DNA without apparent sequence specificity. Thus, additional factors might be...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234206/ https://ncbi.nlm.nih.gov/pubmed/18234858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707260105 |
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