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Vaccine based on a ubiquitous cysteinyl protease and streptococcal pyrogenic exotoxin A protects against Streptococcus pyogenes sepsis and toxic shock
BACKGROUND: The gram-positive bacterium Streptococcus pyogenes is a common pathogen of humans that causes invasive infections, toxic-shock syndrome, rheumatic fever, necrotizing fasciitis and other diseases. Detection of antibiotic resistance in clinical isolates has renewed interest in development...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585077/ https://ncbi.nlm.nih.gov/pubmed/18976486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-8518-6-8 |
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