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Vaccine based on a ubiquitous cysteinyl protease and streptococcal pyrogenic exotoxin A protects against Streptococcus pyogenes sepsis and toxic shock

BACKGROUND: The gram-positive bacterium Streptococcus pyogenes is a common pathogen of humans that causes invasive infections, toxic-shock syndrome, rheumatic fever, necrotizing fasciitis and other diseases. Detection of antibiotic resistance in clinical isolates has renewed interest in development...

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Bibliografiske detaljer
Hovedforfatter: Ulrich, Robert G
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585077/
https://ncbi.nlm.nih.gov/pubmed/18976486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-8518-6-8
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