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Inhibition of cyclooxygenases 1 and 2 by the phospholipase-blocker, arachidonyl trifluoromethyl ketone
BACKGROUND AND PURPOSE: Arachidonyl trifluoromethyl ketone (ATK) is widely used as an inhibitor of cytosolic group IV phospholipase A(2) (cPLA(2)) and calcium-independent group VI phospholipase A(2) (iPLA(2)). ATK thus reduces arachidonic acid (AA) substrate for cyclooxygenase (COX; also known as pr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584923/ https://ncbi.nlm.nih.gov/pubmed/18641670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.304 |
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