12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by western diet

Inflammation is a key pathological process in the progression of atherosclerosis and type 2 diabetes. 12/15-lipoxygenase (12-LO), an enzyme involved in fatty acid metabolism, may contribute to inflammatory damage triggered by stressors such as obesity and insulin resistance. We hypothesized that mic...

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Bibliografische gegevens
Hoofdauteurs: Nunemaker, Craig S., Chen, Meng, Pei, Hong, Kimble, Sarah D., Keller, Susanna R., Carter, Jeffrey D., Yang, Zandong, Smith, Kellie M., Wu, Runpei, Bevard, Melissa H., Garmey, James C., Nadler, Jerry L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584815/
https://ncbi.nlm.nih.gov/pubmed/18780776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90371.2008
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