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12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by western diet

Inflammation is a key pathological process in the progression of atherosclerosis and type 2 diabetes. 12/15-lipoxygenase (12-LO), an enzyme involved in fatty acid metabolism, may contribute to inflammatory damage triggered by stressors such as obesity and insulin resistance. We hypothesized that mic...

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Detalhes bibliográficos
Main Authors: Nunemaker, Craig S., Chen, Meng, Pei, Hong, Kimble, Sarah D., Keller, Susanna R., Carter, Jeffrey D., Yang, Zandong, Smith, Kellie M., Wu, Runpei, Bevard, Melissa H., Garmey, James C., Nadler, Jerry L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584815/
https://ncbi.nlm.nih.gov/pubmed/18780776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90371.2008
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