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Enhanced angiogenesis in obesity and in response to PPARγ activators through adipocyte VEGF and ANGPTL4 production

PPARγ activators such as rosiglitazone (RSG) stimulate adipocyte differentiation and increase subcutaneous adipose tissue mass. However, in addition to preadipocyte differentiation, adipose tissue expansion requires neovascularization to support increased adipocyte numbers. Paradoxically, endothelia...

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Bibliografische gegevens
Hoofdauteurs: Gealekman, Olga, Burkart, Alison, Chouinard, My, Nicoloro, Sarah M., Straubhaar, Juerg, Corvera, Silvia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584813/
https://ncbi.nlm.nih.gov/pubmed/18728224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90345.2008
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