Enhanced angiogenesis in obesity and in response to PPARγ activators through adipocyte VEGF and ANGPTL4 production

PPARγ activators such as rosiglitazone (RSG) stimulate adipocyte differentiation and increase subcutaneous adipose tissue mass. However, in addition to preadipocyte differentiation, adipose tissue expansion requires neovascularization to support increased adipocyte numbers. Paradoxically, endothelia...

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Hlavní autoři: Gealekman, Olga, Burkart, Alison, Chouinard, My, Nicoloro, Sarah M., Straubhaar, Juerg, Corvera, Silvia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584813/
https://ncbi.nlm.nih.gov/pubmed/18728224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90345.2008
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