Enhanced angiogenesis in obesity and in response to PPARγ activators through adipocyte VEGF and ANGPTL4 production

PPARγ activators such as rosiglitazone (RSG) stimulate adipocyte differentiation and increase subcutaneous adipose tissue mass. However, in addition to preadipocyte differentiation, adipose tissue expansion requires neovascularization to support increased adipocyte numbers. Paradoxically, endothelia...

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Main Authors: Gealekman, Olga, Burkart, Alison, Chouinard, My, Nicoloro, Sarah M., Straubhaar, Juerg, Corvera, Silvia
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2008
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584813/
https://ncbi.nlm.nih.gov/pubmed/18728224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90345.2008
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