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Gain of imprinting at chromosome 11p15: A pathogenetic mechanism identified in human hepatocarcinomas

Genomic imprinting is a reversible condition that causes parental-specific silencing of maternally or paternally inherited genes. Analysis of DNA and RNA from 52 human hepatocarcinoma samples revealed abnormal imprinting of genes located at chromosome 11p15 in 51% of 37 informative samples. The most...

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Detalhes bibliográficos
Main Authors: Schwienbacher, Christine, Gramantieri, Laura, Scelfo, Rosaria, Veronese, Angelo, Calin, George A., Bolondi, Luigi, Croce, Carlo M., Barbanti-Brodano, Giuseppe, Negrini, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25848/
https://ncbi.nlm.nih.gov/pubmed/10779553
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