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Chromosomal rearrangements and microRNAs: a new cancer link with clinical implications

There is widespread aberrant expression of mature and/or precursor microRNAs in cancer cells, as microRNAs are deregulated consequent to chromosomal alterations and other genomic abnormalities. The identification of such abnormalities has a clear diagnostic and prognostic significance, and there are...

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Autors principals: Calin, George A., Croce, Carlo M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934569/
https://ncbi.nlm.nih.gov/pubmed/17671640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32577
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