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A catabolic block does not sufficiently explain how 2-deoxy-d-glucose inhibits cell growth
The glucose analogue 2-deoxy-d-glucose (2-DG) restrains growth of normal and malignant cells, prolongs the lifespan of C. elegans, and is widely used as a glycolytic inhibitor to study metabolic activity with regard to cancer, neurodegeneration, calorie restriction, and aging. Here, we report that s...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584745/ https://ncbi.nlm.nih.gov/pubmed/19004802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803090105 |
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