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Orbitofrontal cortex neurons as a common target for classic and glutamatergic antipsychotic drugs

Until recently, all known antipsychotic drugs were thought to block the dopamine D2 receptor. New evidence that agonists of the metabotropic glutamate 2/3 (mGlu2/3) receptors ameliorate psychotic and affective symptoms of schizophrenia suggests that compounds with different molecular targets may act...

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Autori principali: Homayoun, Houman, Moghaddam, Bita
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584724/
https://ncbi.nlm.nih.gov/pubmed/19004793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806669105
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