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Fine-Tuning of Awake Prefrontal Cortex Neurons by Clozapine: Comparison With Haloperidol and N-Desmethylclozapine

BACKGROUND: Mechanisms underlying clozapine’s better clinical efficacy in schizophrenia remain poorly understood. The prefrontal cortex (PFC) has been implicated as a primary site for the therapeutic effects of clozapine; however, evidence for how clozapine influences the activity of PFC neurons in...

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Detalhes bibliográficos
Main Authors: Homayoun, Houman, Moghaddam, Bita
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910426/
https://ncbi.nlm.nih.gov/pubmed/17046721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2006.05.016
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