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NMDA Receptor Hypofunction Produces Opposite Effects on Prefrontal Cortex Interneurons and Pyramidal Neurons

NMDA receptors mediate excitatory postsynaptic potentials throughout the brain but, paradoxically, NMDA receptor antagonists produce cortical excitation in humans and behaving rodents. To elucidate a mechanism for these diverging effects, we examined the effect of use-dependent inhibition of NMDA re...

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Hlavní autoři: Homayoun, Houman, Moghaddam, Bita
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954603/
https://ncbi.nlm.nih.gov/pubmed/17959792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2213-07.2007
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