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Low concentration of arsenite exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity

Epidemiological studies have associated arsenic exposure with many types of human cancers. Arsenic has also been shown to act as a co-carcinogen even at low concentrations. However, the precise mechanism of its co-carcinogenic action is unknown. Recent studies indicate that arsenic can interfere wit...

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Detalhes bibliográficos
Main Authors: Qin, Xu-Jun, Hudson, Laurie G., Liu, Wenlan, Timmins, Graham S., Liu, Ke Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584354/
https://ncbi.nlm.nih.gov/pubmed/18619636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.05.019
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