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Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150(Glued) subunit of dynactin

An increasing number of neurodegenerative diseases are being linked to mutations in genes encoding proteins required for axonal transport and intracellular trafficking. A mutation in p150(Glued), a component of the cytoplasmic dynein/dynactin microtubule motor complex, results in the human neurodege...

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Detalhes bibliográficos
Main Authors: Chevalier-Larsen, Erica S., Wallace, Karen E., Pennise, Cynthia R., Holzbaur, Erika L.F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584350/
https://ncbi.nlm.nih.gov/pubmed/18364389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn092
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