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The C5b-9 membrane attack complex of complement activation localizes to villous trophoblast injury in vivo and modulates human trophoblast function in vitro

The complement system plays an important role in normal human pregnancy. Uncontrolled activation of this system has been associated with many disease states. We tested the hypothesis that the C5b-9 membrane attack complex (MAC) localizes to sites of villous injury and modulates trophoblast function....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rampersad, Roxane, Barton, Aaron, Sadovsky, Yoel, Nelson, D. Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584149/
https://ncbi.nlm.nih.gov/pubmed/18783824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2008.07.008
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