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The C5b-9 membrane attack complex of complement activation localizes to villous trophoblast injury in vivo and modulates human trophoblast function in vitro

The complement system plays an important role in normal human pregnancy. Uncontrolled activation of this system has been associated with many disease states. We tested the hypothesis that the C5b-9 membrane attack complex (MAC) localizes to sites of villous injury and modulates trophoblast function....

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Detalhes bibliográficos
Main Authors: Rampersad, Roxane, Barton, Aaron, Sadovsky, Yoel, Nelson, D. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584149/
https://ncbi.nlm.nih.gov/pubmed/18783824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2008.07.008
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