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The C5b-9 membrane attack complex of complement activation localizes to villous trophoblast injury in vivo and modulates human trophoblast function in vitro

The complement system plays an important role in normal human pregnancy. Uncontrolled activation of this system has been associated with many disease states. We tested the hypothesis that the C5b-9 membrane attack complex (MAC) localizes to sites of villous injury and modulates trophoblast function....

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Bibliografiske detaljer
Main Authors: Rampersad, Roxane, Barton, Aaron, Sadovsky, Yoel, Nelson, D. Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584149/
https://ncbi.nlm.nih.gov/pubmed/18783824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2008.07.008
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