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Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes

OBJECTIVE—To establish the mechanism of the phenotypic switch of adipose tissue macrophages (ATMs) from an alternatively activated (M2a) to a classically activated (M1) phenotype with obesity. RESEARCH DESIGN AND METHODS—ATMs from lean and obese (high-fat diet–fed) C57Bl/6 mice were analyzed by a co...

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Bibliografiska uppgifter
Huvudupphovsmän: Lumeng, Carey N., DelProposto, Jennifer B., Westcott, Daniel J., Saltiel, Alan R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Diabetes Association 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584129/
https://ncbi.nlm.nih.gov/pubmed/18829989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0872
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