Upregulation of Mitochondrial Uncoupling Protein-2 by the AMP-Activated Protein Kinase in Endothelial Cells Attenuates Oxidative Stress in Diabetes

OBJECTIVE—Recent evidence suggests that the AMP-activated protein kinase (AMPK) is an important therapeutic target for diabetes. The present study was conducted to determine how AMPK activation suppressed tyrosine nitration of prostacyclin synthase in diabetes. RESEARCH DESIGN AND METHODS—Confluent...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Xie, Zhonglin, Zhang, Junhua, Wu, Jiliang, Viollet, Benoit, Zou, Ming-Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2008
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584127/
https://ncbi.nlm.nih.gov/pubmed/18835932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0610
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky