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High-efficiency Rosa26 knock-in vector construction for Cre-regulated overexpression and RNAi
INTRODUCTION: Rosa26 is a genomic mouse locus commonly used to knock-in cDNA constructs for ubiquitous or conditional gene expression in transgenic mice. However, the vectors generally used to generate Rosa26 knock-in constructs show instability problems, which have a severe impact on the efficiency...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583990/ https://ncbi.nlm.nih.gov/pubmed/19014667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8417-1-3 |
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