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Mediator Links Epigenetic Silencing of Neuronal Gene Expression with X-Linked Mental Retardation
Mediator occupies a central role in RNA polymerase II transcription as a sensor, integrator, and processor of regulatory signals that converge on protein-coding gene promoters. Compared to its role in gene activation, little is known regarding the molecular mechanisms and biological implications of...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583939/ https://ncbi.nlm.nih.gov/pubmed/18691967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.05.023 |
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