A comparison of BRCT domains involved in nonhomologous end-joining: Introducing the solution structure of the BRCT domain of polymerase lambda

Three of the four family X polymerases, DNA polymerase λ, DNA polymerase µ, and TdT have been associated with repair of double-strand DNA breaks by nonhomologous end-joining. Their involvement in this DNA repair process requires an N-terminal BRCT domain that mediates interaction with other protein...

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Bibliografiske detaljer
Main Authors: Mueller, Geoffrey A., Moon, Andrea F., DeRose, Eugene F., Havener, Jody M., Ramsden, Dale A., Pedersen, Lars C., London, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583787/
https://ncbi.nlm.nih.gov/pubmed/18585102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.04.018
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