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Solution Structure of Polymerase μ’s BRCT Domain Reveals an Element Essential for Its Role in Nonhomologous End Joining
The solution structure and dynamics of the BRCT domain from human DNA polymerase μ, implicated in repair of chromosome breaks by nonhomologous end joining (NHEJ), has been determined using NMR methods. BRCT domains are typically involved in protein—protein interactions between factors required for t...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2653216/ https://ncbi.nlm.nih.gov/pubmed/17915942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7007728 |
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