Escape from HLA-B*08-Restricted CD8 T Cells by Hepatitis C Virus Is Associated with Fitness Costs

The inherent sequence diversity of the hepatitis C virus (HCV) represents a major hurdle for the adaptive immune system to control viral replication. Mutational escape within targeted CD8 epitopes during acute HCV infection has been well documented and is one possible mechanism for T-cell failure. H...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Salloum, Shadi, Oniangue-Ndza, Cesar, Neumann-Haefelin, Christoph, Hudson, Laura, Giugliano, Silvia, aus dem Siepen, Marc, Nattermann, Jacob, Spengler, Ulrich, Lauer, Georg M., Wiese, Manfred, Klenerman, Paul, Bright, Helen, Scherbaum, Norbert, Thimme, Robert, Roggendorf, Michael, Viazov, Sergei, Timm, Joerg
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2008
Предметы:
Pathogenesis and Immunity
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583685/
https://ncbi.nlm.nih.gov/pubmed/18815309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00997-08
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы