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Biochemical and Biophysical Characterization of a Chimeric TRIM21-TRIM5α Protein
The tripartite motif (TRIM) protein, TRIM5α, is an endogenous factor in primates that recognizes the capsids of certain retroviruses after virus entry into the host cell. TRIM5α promotes premature uncoating of the capsid, thus blocking virus infection. Low levels of expression and tendencies to aggr...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583655/ https://ncbi.nlm.nih.gov/pubmed/18799572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01559-08 |
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