Structural Determinant of Human La Protein Critical for Internal Initiation of Translation of Hepatitis C Virus RNA

Human La protein has been implicated in facilitating internal ribosome entry site (IRES)-mediated translation of hepatitis C virus (HCV). Earlier, we demonstrated that the RNA recognition motif (RRM) encompassing residues 112 to 184 of La protein [La (112-184)] interacts with the HCV IRES near the i...

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Detalhes bibliográficos
Main Authors: Mondal, Tanmoy, Ray, Upasana, Manna, Asit Kumar, Gupta, Romi, Roy, Siddhartha, Das, Saumitra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583652/
https://ncbi.nlm.nih.gov/pubmed/18829760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00924-08
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