Computation, prediction, and experimental tests of fitness for bacteriophage T7 mutants with permuted genomes
We created a simulation based on experimental data from bacteriophage T7 that computes the developmental cycle of the wild-type phage and also of mutants that have an altered genome order. We used the simulation to compute the fitness of more than 10(5) mutants. We tested these computations by const...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25836/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792041/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.090101397 |
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