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Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation
MST1, mammalian STE20-like kinase 1, is a serine/threonine kinase that is cleaved and activated by caspases during apoptosis. MST1 is capable of inducing apoptotic morphological changes such as chromatin condensation upon overexpression. In this study, we show that MST1 contains two functional nucle...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC56930/ https://ncbi.nlm.nih.gov/pubmed/11517310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181161698 |
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