Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation

MST1, mammalian STE20-like kinase 1, is a serine/threonine kinase that is cleaved and activated by caspases during apoptosis. MST1 is capable of inducing apoptotic morphological changes such as chromatin condensation upon overexpression. In this study, we show that MST1 contains two functional nucle...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ura, Seiji, Masuyama, Norihisa, Graves, Jonathan D., Gotoh, Yukiko
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC56930/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11517310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.181161698
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