The Cryptococcus neoformans Rho-GDP Dissociation Inhibitor Mediates Intracellular Survival and Virulence

Rho-GDP dissociation inhibitors (Rho-GDI) are repressors of Rho-type monomeric GTPases that control fundamental cellular processes, such as cytoskeletal arrangement, vesicle trafficking, and polarized growth. We identified and altered the expression of the gene encoding a Rho-GDI homolog in the huma...

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Bibliographic Details
Main Authors: Price, Michael S., Nichols, Connie B., Alspaugh, J. Andrew
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583580/
https://ncbi.nlm.nih.gov/pubmed/18779335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00896-08
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