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Porphyromonas gingivalis, Gamma Interferon, and a Proapoptotic Fibronectin Matrix Form a Synergistic Trio That Induces c-Jun N-Terminal Kinase 1-Mediated Nitric Oxide Generation and Cell Death

During infection and inflammation, bacterial and inflammatory proteases break down extracellular matrices into macromolecular fragments. Fibronectin fragments are associated with disease severity in arthritis and periodontitis. The mechanisms by which these fragments contribute to disease pathogenes...

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Detalhes bibliográficos
Main Authors: Ghosh, Abhijit, Park, Ji Young, Fenno, Christopher, Kapila, Yvonne L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583576/
https://ncbi.nlm.nih.gov/pubmed/18838522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00625-08
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