Modulation of an Interleukin-12 and Gamma Interferon Synergistic Feedback Regulatory Cycle of T-Cell and Monocyte Cocultures by Porphyromonas gingivalis Lipopolysaccharide in the Absence or Presence of Cysteine Proteinases

Interleukin 12 (IL-12) is an efficient inducer and enhancer of gamma interferon (IFN-γ) production by both resting and activated T cells. There is evidence that human monocytes exposed to IFN-γ have enhanced ability to produce IL-12 when stimulated with lipopolysaccharide (LPS). In this study, it wa...

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Bibliographic Details
Main Authors: Yun, Peter L. W., DeCarlo, Arthur A., Collyer, Charles, Hunter, Neil
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC128344/
https://ncbi.nlm.nih.gov/pubmed/12228299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.10.5695-5705.2002
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