Optimization of the Oligonucleotide Ligation Assay, a Rapid and Inexpensive Test for Detection of HIV-1 Drug Resistance Mutations, for Non-North American Variants

OBJECTIVE: We evaluated the feasibility of the oligonucleotide ligation assay (OLA), a specific, sensitive, and economical ligase-based point mutation assay designed to detect HIV-1 drug–resistance mutations at 12 codons of HIV-1 subtype B pol, for potential use in resource-poor settings. METHODS: S...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Beck, Ingrid A., Crowell, Claudia, Kittoe, Robin, Bredell, Helba, Machaba, Molefe, Willamson, Carolyn, Janssens, Wouter, Jallow, Sabelle, van der Groen, Guido, Shao, Yiming, Jacob, Mini, Samuel, N. M., de Rivera, Ivette Lorenzana, Ngo-Giang-Huong, Nicole, Cassol, Sharon, Alemnji, George, Frenkel, Lisa M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583356/
https://ncbi.nlm.nih.gov/pubmed/18614915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31817ed7d7
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