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Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes

Notch1-deficient epidermal keratinocytes become progressively hyperplastic, eventually producing tumors. In contrast, we observed that Notch1 deficient hair matrix keratinocytes have lower mitotic rates, resulting in smaller follicles with fewer cells. In addition, the ratio of melanocytes to kerati...

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書誌詳細
主要な著者: Lee, Jonghyeob, Basak, Jacob M., Demehri, Shadmehr, Kopan, Raphael
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583345/
https://ncbi.nlm.nih.gov/pubmed/17611229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.02868
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