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Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes
Notch1-deficient epidermal keratinocytes become progressively hyperplastic, eventually producing tumors. In contrast, we observed that Notch1 deficient hair matrix keratinocytes have lower mitotic rates, resulting in smaller follicles with fewer cells. In addition, the ratio of melanocytes to kerati...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583345/ https://ncbi.nlm.nih.gov/pubmed/17611229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.02868 |
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