GASTRO-D-01631R1 Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells

BACKGROUND & AIMS: CXCL12 and CXCR4 signaling plays critical roles in development, homeostasis, and tumor metastasis. Previously we have shown that epigenetic silencing of CXCL12 in colorectal and mammary carcinoma promotes metastasis. Anoikis is an essential process of colonic epithelial turnov...

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Main Authors: Wendt, Michael K., Drury, Luke J., Vongsa, Rebecca A., Dwinell, Michael B.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583344/
https://ncbi.nlm.nih.gov/pubmed/18558091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.05.033
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