The p38 Mitogen-activated Protein Kinase Augments Nucleotide Excision Repair by Mediating DDB2 Degradation and Chromatin Relaxation

The p38 MAPK is a family of serine/threonine protein kinases that play important roles in cellular responses to external stress signals, e.g. UV irradiation. To assess the role of p38 MAPK pathway in nucleotide excision repair (NER), the most versatile DNA repair pathway, we determined the efficienc...

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Qun, Barakat, Bassant M., Qin, Song, Ray, Alo, El-Mahdy, Mohamed A., Wani, Gulzar, Arafa, El-Shaimaa, Mir, Safita N., Wang, Qi-En, Wani, Altaf A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583317/
https://ncbi.nlm.nih.gov/pubmed/18806262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803963200
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