The p38 Mitogen-activated Protein Kinase Augments Nucleotide Excision Repair by Mediating DDB2 Degradation and Chromatin Relaxation

The p38 MAPK is a family of serine/threonine protein kinases that play important roles in cellular responses to external stress signals, e.g. UV irradiation. To assess the role of p38 MAPK pathway in nucleotide excision repair (NER), the most versatile DNA repair pathway, we determined the efficienc...

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Bibliographic Details
Main Authors: Zhao, Qun, Barakat, Bassant M., Qin, Song, Ray, Alo, El-Mahdy, Mohamed A., Wani, Gulzar, Arafa, El-Shaimaa, Mir, Safita N., Wang, Qi-En, Wani, Altaf A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583317/
https://ncbi.nlm.nih.gov/pubmed/18806262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803963200
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