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VHL Type 2B Mutations Retain VBC Complex Form and Function
BACKGROUND: von Hippel-Lindau disease is characterized by a spectrum of hypervascular tumors, including renal cell carcinoma, hemangioblastoma, and pheochromocytoma, which occur with VHL genotype-specific differences in penetrance. VHL loss causes a failure to regulate the hypoxia inducible factors...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583047/ https://ncbi.nlm.nih.gov/pubmed/19030229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003801 |
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