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VHL Inactivation in Renal Cell Carcinoma: Implications for Diagnosis, Prognosis, and Treatment

Clear cell renal cell carcinoma (ccRCC) provides a tumor paradigm for the integration of genetics, molecular biology, therapeutic target validation, and the introduction of high impact treatment strategies. Most cases of sporadic as well as familial ccRCC acquire somatic inactivating mutations of th...

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Bibliografiska uppgifter
Huvudupphovsmän: Rathmell, W. Kimryn, Chen, Shufen
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873028/
https://ncbi.nlm.nih.gov/pubmed/18095884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.8.1.63
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