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VHL Inactivation in Renal Cell Carcinoma: Implications for Diagnosis, Prognosis, and Treatment
Clear cell renal cell carcinoma (ccRCC) provides a tumor paradigm for the integration of genetics, molecular biology, therapeutic target validation, and the introduction of high impact treatment strategies. Most cases of sporadic as well as familial ccRCC acquire somatic inactivating mutations of th...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873028/ https://ncbi.nlm.nih.gov/pubmed/18095884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.8.1.63 |
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