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An Ancient Evolutionary Origin of Genes Associated with Human Genetic Diseases

Several thousand genes in the human genome have been linked to a heritable genetic disease. The majority of these appear to be nonessential genes (i.e., are not embryonically lethal when inactivated), and one could therefore speculate that they are late additions in the evolutionary lineage toward h...

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Bibliografiske detaljer
Main Authors: Domazet-Lošo, Tomislav, Tautz, Diethard
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582983/
https://ncbi.nlm.nih.gov/pubmed/18820252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msn214
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