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Phylostratigraphic tracking of cancer genes suggests a link to the emergence of multicellularity in metazoa

BACKGROUND: Phylostratigraphy is a method used to correlate the evolutionary origin of founder genes (that is, functional founder protein domains) of gene families with particular macroevolutionary transitions. It is based on a model of genome evolution that suggests that the origin of complex pheno...

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Main Authors: Domazet-Lošo, Tomislav, Tautz, Diethard
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880965/
https://ncbi.nlm.nih.gov/pubmed/20492640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-8-66
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