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An Ancient Evolutionary Origin of Genes Associated with Human Genetic Diseases

Several thousand genes in the human genome have been linked to a heritable genetic disease. The majority of these appear to be nonessential genes (i.e., are not embryonically lethal when inactivated), and one could therefore speculate that they are late additions in the evolutionary lineage toward h...

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Autors principals: Domazet-Lošo, Tomislav, Tautz, Diethard
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582983/
https://ncbi.nlm.nih.gov/pubmed/18820252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msn214
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