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Uncorrected Nucleotide Bias in mtDNA Can Mimic the Effects of Positive Darwinian Selection

The relative rates of nucleotide substitution at synonymous and nonsynonymous sites within protein-coding regions have been widely used to infer the action of natural selection from comparative sequence data. It is known, however, that mutational and repair biases can affect rates of evolution at bo...

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Detalhes bibliográficos
Main Authors: Albu, Mihai, Min, Xiang Jia, Hickey, Donal, Golding, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582980/
https://ncbi.nlm.nih.gov/pubmed/18842686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msn224
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