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Uncorrected Nucleotide Bias in mtDNA Can Mimic the Effects of Positive Darwinian Selection

The relative rates of nucleotide substitution at synonymous and nonsynonymous sites within protein-coding regions have been widely used to infer the action of natural selection from comparative sequence data. It is known, however, that mutational and repair biases can affect rates of evolution at bo...

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Autors principals: Albu, Mihai, Min, Xiang Jia, Hickey, Donal, Golding, Brian
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582980/
https://ncbi.nlm.nih.gov/pubmed/18842686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msn224
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