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Generating iPS Cells from MEFS through Forced Expression of Sox-2, Oct-4, c-Myc, and Klf4

Pluripotency can be induced in differentiated murine by viral transduction of Oct4, Sox2, Klf4, and c-Myc (Takahashi and Yamanaka, 2006; Wernig, et al., 2007; Okita, et al., 2007; Maherali, et al., 2007). We have devised a reprogramming strategy in which these four transcription factors are expresse...

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Main Authors: Welstead, G. Grant, Brambrink, Tobias, Jaenisch, Rudolf
格式: Artigo
語言:Inglês
出版: MyJove Corporation 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582849/
https://ncbi.nlm.nih.gov/pubmed/19066578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/734
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